Other Names Abelson murine leukemia viral oncogene 1; ABL1; c-ABL; EC 2.7.10.2; JTK7; p150; proto-oncogene tyrosine-protein kinase ABL1; v-abl Abelson murine leukemia viral oncogene 1
All Sites Human: Tyr393/ Tyr439; Mouse: Tyr393/ Tyr439; Rat: Tyr412/-
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Abl around the phosphorylation site of tyrosine 393/412 (D-T-YP-T-A).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Abl (Phospho-Tyr393/412) antibody detects endogenous levels of Abl only when phosphorylated at tyrosine 393/412.
ReferencesLi G.Y., Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
Nagase T., DNA Res. 6:63-70(1999).
Krapivinsky G., Neuron 43:563-574(2004).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells