Other Names EC 3.6.1.-, RECQ3, RECQL2, RECQL3, Werner Syndrome helicase
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Werner Syndrome Helicase around the phosphorylation site of serine 1141 (S-S-SP-Q-P).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Werner Syndrome Helicase (Phospho-Ser1141) antibody detects endogenous levels of Werner Syndrome Helicase only when phosphorylated at serine 1141.
ReferencesYu C.-E., Science 272:258-262(1996).
Marciniak R.A., Proc. Natl. Acad. Sci. U.S.A. 95:6887-6892(1998).
Kusano K., Genetics 151:1027-1039(1999).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells