Other Names GEF-H1, GEFH1, Guanine nucleotide exchange factor GEF-H1, proliferating cell nucleolar antigen p40, rho/rac guanine nucleotide exchange factor 2
All Sites Human: Ser885; Mouse: Ser885
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Rho/Rac Guanine Nucleotide Exchange Factor 2 around the phosphorylation site of serine 885 (R-R-SP-L-P).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Rho/Rac Guanine Nucleotide Exchange Factor 2 (Phospho-Ser885) antibody detects endogenous levels of Rho/Rac Guanine Nucleotide Exchange Factor 2 only when phosphorylated at serine 885.
ReferencesRen Y., J. Biol. Chem. 273:34954-34960(1998).
Krendel M., Nat. Cell Biol. 4:294-301(2002).
Ishikawa K., DNA Res. 5:169-176(1998).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells