Other Names Cell cycle regulatory protein P95; NBN; NBS; NIBRIN; Nijmegen breakage syndrome 1 (nibrin); NIJMEGEN BREAKAGE syndrome protein 1; p95-NBS1
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Nibrin around the phosphorylation site of serine 278 (T-N-SP-Q-T).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Nibrin (Phospho-Ser278) antibody detects endogenous levels of Nibrin only when phosphorylated at serine 278.
ReferencesVaron R., Cell 93:467-476(1998).
Carney J.P., Cell 93:477-486(1998).
Matsuura S., Nat. Genet. 19:179-181(1998).