Other Names Glial fibrillary acidic protein, astrocyte
All Sites Human: Ser38; Mouse: Ser35
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human GFAP around the phosphorylation site of serine 38 (R-L-SP-L-A).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity GFAP (Phospho-Ser38) antibody detects endogenous levels of GFAP only when phosphorylated at serine 38.
ReferencesBrenner M., Brain Res. Mol. Brain Res. 7:277-286(1990).
Ota T., Nat. Genet. 36:40-45(2004).
Nielsen A.L., J. Biol. Chem. 277:29983-29991(2002).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells