Other Names EC 2.7.7.49, EST2, HEST2, TCS1, TERT, TRT, Telomerase catalytic subunit, Telomerase reverse transcriptase
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human TERT around the phosphorylation site of serine 824 (G-K-SP-Y-V).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity TERT (Phospho-Ser824) antibody detects endogenous levels of TERT only when phosphorylated at serine 824.
ReferencesNakamura T.M., Science 277:955-959(1997).
Bacchetti S., Cell 90:785-795(1997).
Hisatomi H., Neoplasia 5:193-197(2003).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells