Other Names EC 2.7.7.49, EST2, HEST2, TCS1, TERT, TRT, Telomerase catalytic subunit, Telomerase reverse transcriptase
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Telomerase around the phosphorylation site of serine 227 (G-G-SP-A-S).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Telomerase (Phospho-Ser227) antibody detects endogenous levels of Telomerase only when phosphorylated at serine 227.
ReferencesNakamura T.M., Science 277:955-959(1997).
Meyerson M., Cell 90:785-795(1997).
Wick M., Gene 232:97-106(1999).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells