Other Names 1- phosphatidylinositol-4-phosphate 5-kinase, EC 2.7.1.68, FYV1, FYVE finger-containing phosphoinositide kinase, KIAA0981, PIKfyve, PIP5K3, PtdIns(4)P-5- kinase, p235
All Sites Human: Ser307; Mouse: Ser318
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PIP5K around the phosphorylation site of serine 307 (S-A-SP-I-T).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PIP5K (Phospho-Ser307) antibody detects endogenous levels of PIP5K only when phosphorylated at serine 307.
ReferencesOta T., Nat. Genet. 36:40-45(2004).
Nagase T., DNA Res. 6:63-70(1999).
Olsen J.V., Cell 127:635-648(2006).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells