Other Names neoplastic transformation inhibitor; nuclear antigen H731-like; programmed cell death protein 4
All Sites Human: Ser67; Mouse: Ser67; Rat: Ser67
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PDCD4 around the phosphorylation site of serine 67 (K-N-SP-S-R).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PDCD4 (Phospho-Ser67) antibody detects endogenous levels of PDCD4 only when phosphorylated at serine 67.
ReferencesMatsuhashi S., Res. Commun. Biochem. Cell Mol. Biol. 1:109-120(1997).
Azzoni L., J. Immunol. 161:3493-3500(1998).
Deloukas P., Nature 429:375-381(2004).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells