Other Names FA; Fa; FA-H; FA1; FAA; FACA; FAH; FANCH; Fanconi anemia group A protein; Fanconi anemia, complementation group A
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human FANCA around the phosphorylation site of serine 1149 (D-P-SP-L-M).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity FANCA (Phospho-Ser1149) antibody detects endogenous levels of FANCA only when phosphorylated at serine 1149.
ReferencesLo Ten Foe J.R., Nat. Genet. 14:320-323(1996).
Ianzano L., Genomics 41:309-314(1997).
Ricke D.O., Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells