Other Names CDK5, CRK6, Cell division protein kinase 5, EC 2.7.11.22, PSSALRE, TAU protein kinase II catalytic subunit, TPKII catalytic subunit, Tau protein kinase II catalytic subunit, kinase Cdk5
All Sites Human: Tyr15; Mouse: Tyr15; Rat: Tyr15
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CDK5 around the phosphorylation site of tyrosine 15 (G-T-YP-G-T).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity CDK5 (Phospho-Tyr15) antibody detects endogenous levels of CDK5 only when phosphorylated at tyrosine 15.
ReferencesMeyerson M., EMBO J. 11:2909-2917(1992).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Honma N., Biochem. Biophys. Res. Commun. 310:398-404(2003).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells