Other Names AIE1, AIE2, AURKC, Aurora-C, Aurora/Ipl1-related kinase 3, Aurora/Ipl1/Eg2 protein 1, Aurora/Ipl1/Eg2 protein 2, EC 2.7.11.1, STK13, STKD, Serine/threonine protein kinase 13, kinase AIK3
All Sites Human: Thr236/202; Mouse: Thr241/175; Rat: Thr239/175
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human AurB/C around the phosphorylation site of threonine 236/202 (C-G-TP-L-D).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity AurB/C (Phospho-Thr236/202) antibody detects endogenous levels of AurB/C only when phosphorylated at threonine 236/202.
ReferencesSteven L. Warner. Mol. Cancer Ther., Oct 2006; 5: 2450 - 2458.
Adrianne E. Hontz. AACR Meeting Abstracts, Apr 2005; 2005: 492.
Adrianne E. Hontz. AACR Meeting Abstracts, Apr 2006; 2006: 1326.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells