Other Names DNA topoisomerase II, DNA topoisomerase II-alpha, EC 5.99.1.3, P11388-1, TOP-2, TOP2, TOP2A, TP2A, alpha isozyme
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human TOP2A around the phosphorylation site of serine 1106 (E-E-SP-D-N).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/Sensitivity TOP2A (Ab-1106) antibody detects endogenous levels of total TOP2A protein.
ReferencesTsai-Pflugfelder M., Proc. Natl. Acad. Sci. U.S.A. 85:7177-7181(1988).
Wasserman R.A., Cancer Res. 53:3591-3596(1993).
Lang A.J., Gene 221:255-266(1998).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells