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Primary Antibodies
TOP2A (Phospho-Ser1106) Antibody
Human (Identities = 100%, Positives = 100%); Mouse (Identities = 90%, Positives = 90%)
WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000
$225/ 100μg
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Other Names alpha isozyme; DNA topoisomerase II; DNA topoisomerase II-alpha; EC 5.99.1.3; P11388-1; TOP-2; TOP2; TOP2A; TP2A
All Sites Human: Ser1106; Mouse: Ser1105
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human TOP2A around the phosphorylation site of serine 1106 (E-E-SP-D-N).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity TOP2A (Phospho-Ser1106) antibody detects endogenous levels of TOP2A only when phosphorylated at serine 1106.
ReferencesTsai-Pflugfelder M., Proc. Natl. Acad. Sci. U.S.A. 85:7177-7181(1988).
Wasserman R.A., Cancer Res. 53:3591-3596(1993).
Lang A.J., Gene 221:255-266(1998).
Wasserman R.A., Cancer Res. 53:3591-3596(1993).
Lang A.J., Gene 221:255-266(1998).
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using TOP2A (Phospho- Ser1106) antibody.
Western blot analysis of extracts from Jurkat cells, treated with paclitaxel (1uM, 24hours), using TOP2A (Phospho- Ser1106) antibody.
Conjugated Antibody
This product is also available conjugated. Format: E11-1130A-Conjugate. Price: $485 / Size: 100μl.
E11-1130A-FITC$485 / 100μlE11-1130A-Biotin$485 / 100μlE11-1130A-HRP$485 / 100μlE11-1130A-AP$485 / 100μlE11-1130A-AF350$485 / 100μlE11-1130A-AF405M$485 / 100μlE11-1130A-AF488$485 / 100μlE11-1130A-AF514$485 / 100μlE11-1130A-AF532$485 / 100μlE11-1130A-AF555$485 / 100μlE11-1130A-AF568$485 / 100μlE11-1130A-AF405S$485 / 100μlE11-1130A-AF405L$485 / 100μlE11-1130A-AF546$485 / 100μlE11-1130A-AF594$485 / 100μlE11-1130A-AF610$485 / 100μlE11-1130A-AF635$485 / 100μlE11-1130A-AF647$485 / 100μlE11-1130A-AF680$485 / 100μlE11-1130A-AF700$485 / 100μlE11-1130A-AF750$485 / 100μlE11-1130A-AF790$485 / 100μlE11-1130A-APC$485 / 100μlE11-1130A-PE$485 / 100μlE11-1130A-Cy3$485 / 100μlE11-1130A-Cy5$485 / 100μlE11-1130A-Cy5.5$485 / 100μlE11-1130A-Cy7$485 / 100μlE11-1130A-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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