Other Names B-cell surface antigen CD40; Bp50; CD40 antigen; CD40L receptor; CDw40; TNR5; tumor necrosis factor receptor superfamily member 5
All Sites Human: Thr254; Mouse: Thr255
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human TNFRSF5 around the phosphorylation site of threonine 254 (Q-E-TP-L-H).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity TNFRSF5 (Phospho-Thr254) antibody detects endogenous levels of TNFRSF5 only when phosphorylated at threonine 254.
ReferencesStamenkovic I., EMBO J. 8:1403-1410(1989).
Tone M., Proc. Natl. Acad. Sci. U.S.A. 98:1751-1756(2001).
Deloukas P., Nature 414:865-871(2001).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells