Other Names EC 2.7.11.30, TGF-beta receptor type II precursor, TGF-beta type II receptor, TGF-betaR2, TGFR-2, TGFR2, kinase TGF-beta-R2
All Sites Human: Ser225; Mouse: Ser250
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human TGF β Receptor II around the phosphorylation site of serine 225/250 (D-R-SP-D-I).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity TGF β Receptor II (Phospho-Ser225/250) antibody detects endogenous levels of TGF β Receptor II only when phosphorylated at serine 225/250.
ReferencesRC Tripathi, Invest. Ophthalmol. Vis. Sci., Jan 1993; 34: 260.
N Chegini, Endocrinology, Jul 1994; 135: 439.
GW Mulheron, Endocrinology, Dec 1992; 131: 2609.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells