Other Names ADRB2; ALK-5; Activin receptor-like kinase 5; ESK2; SKR4; TGF-beta receptor type I precursor; TGF-beta type I receptor; TGF-betaR1; TGFR-1; TGFR1; kinase TGF-beta-R1; receptor R4
All Sites Human: Ser165; Mouse: Ser165; Rat: Ser163
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human TGF β Receptor I around the phosphorylation site of serine 165 (D-P-SP-L-D).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity TGF β Receptor I (Phospho-Ser165) antibody detects endogenous levels of TGF β Receptor I only when phosphorylated at serine 165.
ReferencesFranzen P., Cell 75:681-692(1993).
Vellucci V.F., Genomics 46:278-283(1997).
Lynch M.A., Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
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Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells