Other Names ADRB2, Alpha-PAK, CDC42/RAC effector kinase PAK-A, EC 2.7.11.1, P65-PAK, P68-PAK, PAK 1, PAK-1, PAKA, Protein kinase MUK2, kinase PAK1, p21-activated kinase 1
All Sites Human: Ser199; Mouse: Ser199; Rat: Ser198
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PAK1/2 around the phosphorylation site of serine 199 (T-K-SP-V-Y).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PAK1/2 (Phospho-Ser199) antibody detects endogenous levels of PAK1/2 only when phosphorylated at serine 199.
ReferencesBrown J.L., Curr. Biol. 6:598-605(1996).
Sells M.A., Curr. Biol. 7:202-210(1997).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
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Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells