Other Names MOES, MSN, Membrane-organizing extension spike protein
All Sites Human: Thr558; Mouse: Thr558; Rat: Thr558
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Moesin/Ezrin/Radixin around the phosphorylation site of threonine 558 (Y-K-TP-L-R).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody againstnon-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Moesin/Ezrin/Radixin (Phospho-Thr558) antibody detects endogenous levels of Moesin/Ezrin/Radixin only when phosphorylated at threonine 558.
ReferencesLankes W.T., Proc. Natl. Acad. Sci. U.S.A. 88:8297-8301(1991).
Ross M.T., Nature 434:325-337(2005).
Gevaert K., Nat. Biotechnol. 21:566-569(2003).
Kim S.C., Mol. Cell 23:607-618(2006).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells