Other Names 3CH134, CL100, DUS1, DUSP1, Dual specificity protein phosphatase 1, Dual specificity protein phosphatase hVH1, EC 3.1.3.16, EC 3.1.3.48, MAP kinase phosphatase-1, MKP1, PTPN10, PTPN16, Protein-tyrosine phosphatase 3CH134, Protein-tyrosine phosphatase CL100, Protein-tyrosine phosphatase ERP, VH1
All Sites Human: Ser359; Mouse: Ser359
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human MKP1 around the phosphorylation site of serine 359(L-Q-SP-P-I).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity MKP1 (Phospho-Ser359) antibody detects endogenous levels of MKP1 only when phosphorylated at serine 359.
ReferencesKeyes S.M., Nature 359:644-647(1992).
Kwak S.P., J. Biol. Chem. 269:3596-3604(1994).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells