Other Names EAT/MCL-1 protein, Induced myeloid leukemia cell differentiation protein Mcl-1, Myeloid cell leukemia sequence 1
All Sites Human: Ser159; Mouse: Ser159
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human MCL1 around the phosphorylation site of serine 159 (D-G-SP-L-P).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity MCL1 (Phospho-Ser159) antibody detects endogenous levels of MCL1 only when phosphorylated at serine 3159.
ReferencesAlfredo De Biasio, J. Biol. Chem., Jun 2007; 10.1074/jbc.M700938200.
Potchanapond Graidist, J. Biol. Chem., Sep 2004; 279: 40868 - 40875.
Kenichi Fujise, J. Biol. Chem., Dec 2000; 275: 39458.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells