Other Names MAP/microtubule affinity-regulating kinase 1, MARK
All Sites Human: Thr215/208/235/215; Mouse: Thr215/208/212/215; Rat: Thr215/208/212/-
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human MARK1/2/3/4 around the phosphorylation site of threonine 215 (L-D-TP-F-C).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity MARK1/2/3/4 (Phospho-Thr215) antibody detects endogenous levels of MARK1/2/3/4 only when phosphorylated at threonine 215.
ReferencesLizcano J.M., EMBO J. 23:833-843(2004).
Zhou H.J., Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
Nagase T., DNA Res. 7:143-150(2000).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells