Other Names KCNQ3, KQT-like 3, potassium channel alpha subunit KvLQT3, potassium voltage-gated channel subfamily KQT member 3, voltage-gated potassium channel subunit Kv7.3
All Sites Human: Thr246; Mouse: Thr247; Rat: Thr247
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Kv7.3/KCNQ3 around the phosphorylation site of threonine 246 (G-G-TP-W-K).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Kv7.3/KCNQ3 (Phospho-Thr246) antibody detects endogenous levels of Kv7.3/KCNQ3 only when phosphorylated at threonine 246.
ReferencesSchroeder B.C., Nature 396:687-690(1998).
Charlier C., Nat. Genet. 18:53-55(1998).
Yang W.-P., J. Biol. Chem. 273:19419-19423(1998).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells