Other Names Eg5, KIFL1, KNSL1, Kinesin-like protein 1, Kinesin-like protein KIF11, Kinesin-like spindle protein HKSP, Kinesin-related mitotic motor protein, Kinesin-related motor protein Eg5, TRIP5, Thyroid receptor interacting protein 5
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human KIF11/Eg5 around the phosphorylation site of threonine 926 (G-T-TP-P-Q).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity KIF11/Eg5 (Phospho-Thr926) antibody detects endogenous levels of KIF11/Eg5 only when phosphorylated at threonine 926.
ReferencesBlangy A., Cell 83:1159-1169(1995).
Whitehead C.M., J. Cell Sci. 111:2551-2561(1998).
Hunt S.E., Nature 429:375-381(2004).
Lee J.W., Mol. Endocrinol. 9:243-254(1995).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells