Other NamesEC 2.7.10.2, JAK-3, JAK3, Janus kinase 3, L-JAK, Leukocyte janus kinase, kinase Jak3 EC 2.7.10.2, JAK-3, JAK3, Janus kinase 3, L-JAK, Leukocyte janus kinase, kinase Jak3
All SitesHuman: Tyr785; Mouse: Tyr996; Rat: Tyr781
Storage/StabilityStore at -20℃/1 year
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human JAK3 around the phosphorylation site of tyrosine 785 (S-D-YP-E-L).
PurificationThe antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityJAK3 (Phospho-Tyr785) antibody detects endogenous levels of JAK3 only when phosphorylated at tyrosine 785.
ReferencesKawamura M., Proc. Natl. Acad. Sci. U.S.A. 91:6374-6378(1994).
Lai K.S., J. Biol. Chem. 270:25028-25036(1995).
Endo K., FEBS Lett. 477:55-61(2000).
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