Other Names EC 2.7.11.1, IL1RAK, IRAK, IRAK-1, Interleukin-1 receptor-associated kinase 1, Pelle-like protein kinase, kinase IRAK1, mPLK
All Sites Human: Thr100; Mouse: Thr100
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IRAK1 around the phosphorylation site of threonine 100 (I-I-TP-A-W).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity IRAK1 (Phospho-Thr100) antibody detects endogenous levels of IRAK1 only when phosphorylated at threonine 100.
ReferencesCao Z., Science 271:1128-1131(1996).
Reichwald K., Mamm. Genome 11:182-190(2000).
Jensen L.E., J. Biol. Chem. 276:29037-29044(2001).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells