Other Names CDw128b, CXCR-2, CXCR2, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8 receptor type 2, IL8RB, interleukin-8 receptor B
All Sites Human: Ser347; Mouse: Ser346
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IL-8Rβ/CDw128β around the phosphorylation site of serine 347 (R-P-SP-F-V).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity IL-8Rβ/CDw128β (Phospho-Ser347) antibody detects endogenous levels of IL-8Rβ/CDw128β only when phosphorylated at serine 347.
ReferencesMurphy P.M., Science 253:1280-1283(1991).
Cerretti D.P., Mol. Immunol. 30:359-367(1993).
Ahuja S.K., J. Biol. Chem. 269:26381-26389(1994).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells