Other Names CD127 antigen, CDw127, IL-7R alpha, IL7RA, interleukin-7 receptor alpha chain
All Sites Human: Tyr449; Mouse: Tyr449
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IL-7R/CD127 around the phosphorylation site of tyrosine 449 (E-A-YP-V-T).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity IL-7R/CD127 (Phospho-Tyr449) antibody detects endogenous levels of IL-7R/CD127 only when phosphorylated at tyrosine 449.
ReferencesD Benjamin, J. Immunol., May 1994; 152: 4749.
TH Page, J. Immunol., Nov 1993; 151: 4753.
Kohtaro Fujihashi, PNAS, Apr 1996; 93: 3613.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells