Other Names 582J2.1, CD124 antigen, IL-4R-alpha, IL4RA, Interleukin-4 receptor alpha chain precursor
All Sites Human: Tyr497; Mouse: Tyr500
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IL-4R/CD124 around the phosphorylation site of tyrosine 497 (P-A-YP-R-S).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity IL-4R/CD124 (Phospho-Tyr497) antibody detects endogenous levels of IL-4R/CD124 only when phosphorylated at tyrosine 497.
ReferencesIdzerda R.L., J. Exp. Med. 171:861-873(1990).
Galizzi J.-P., Int. Immunol. 2:669-675(1990).
Loftus B.J., Genomics 60:295-308(1999).
Kruse S., Int. Immunol. 11:1965-1970(1999).