Other Names CD122 antigen, High affinity IL-2 receptor beta subunit, IL-2 receptor, IL-2R beta, Interleukin-2 receptor beta chain precursor, P70-75
All Sites Human: Tyr364; Mouse: Tyr367
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IL-2Rβ/CD122 around the phosphorylation site of tyrosine 364 (Q-G-YP-F-F).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity IL-2Rβ/CD122 (Phospho-Tyr364) antibody detects endogenous levels of IL-2Rβ/CD122 only when phosphorylated at tyrosine 364.
ReferencesHatakeyama M., Science 244:551-556(1989).
Dunham I., Nature 402:489-495(1999).
Mulloy J.C., J. Virol. 70:3599-3605(1996).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells