Other Names I10R, I10R1, IL-10R alpha, IL-10R1, IL10R, IL10RA, Interleukin-10 receptor alpha chain precursor
All Sites Human: Tyr493; Mouse: Tyr493
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IL-10Rα around the phosphorylation site of tyrosine 496 (K-G-YP-L-K).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity IL-10Rα (Phospho-Tyr496) antibody detects endogenous levels of IL-10Rα only when phosphorylated at tyrosine 496.
ReferencesLiu Y., J. Immunol. 152:1821-1829(1994).
Zhang Z., Protein Sci. 13:2819-2824(2004).
Josephson K., Immunity 15:35-46(2001).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells