Other Names IBP-3, IBP3, IGF-binding protein 3, IGFBP3, Insulin-like growth factor binding protein 3 precursor
All Sites Human: Ser183; Mouse: Ser183
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IGFBP-3 around the phosphorylation site of serine 183 (K-D-SP-Q-R).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity IGFBP-3 (Phospho-Ser183) antibody detects endogenous levels of IGFBP-3 only when phosphorylated at serine 183.
ReferencesC. Schmid, Am J Physiol Endocrinol Metab, Aug 1994; 267: E226 - E233.
Hanh Le, Am J Physiol Endocrinol Metab, May 2006; 290: E952 - E960.
C. A. Gibson, J Anim Sci, Jun 1999; 77: 1547 - 1557.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells