Other Names HNRNPC, HNRPC, Heterogeneous nuclear ribonucleoproteins C1/C2, ROC, hnRNP C1 / hnRNP C2, hnRNP-C1/C2
All Sites Human: Ser260; Mouse: Ser268
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human hnRNP C1/2 around the phosphorylation site of serine 260 (D-D-SP-A-E).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity hnRNP C1/2 (Phospho-Ser260) antibody detects endogenous levels of hnRNP C1/2 only when phosphorylated at serine 260.
ReferencesThe MGC Project Team, Genome Res. 14:2121-2127(2004).
Merrill B.M., Nucleic Acids Res. 17:8441-8449(1989).
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells