Other Names CASP-2, Caspase-2 precursor, EC 3.4.22.-, ICH- 1L/1S, ICH-1 protease, ICH1
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Caspase 2 around the phosphorylation site of serine 157 (R-L-SP-T-D).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Caspase 2 (Phospho-Ser157) antibody detects endogenous levels of Caspase 2 only when phosphorylated at serine 157.
ReferencesWang L., Cell 78:739-750(1994).
Hillier L.W., Nature 424:157-164(2003).
Droin N., Cancer Res. 60:7039-7047(2000).