Other Names AIK2, AIM-1, AIM1, ARK2, AURKB, Aurora- and Ipl1-like midbody-associated protein 1, Aurora-B, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, EC 2.7.11.1, STK-1, STK12, Serine/threonine protein kinase 12
All Sites Human: Thr232; Mouse: Thr237; Rat: Thr235
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human AurB around the phosphorylation site of threonine 232 (R-K-TP-M-C).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity AurB (Phospho-Thr232) antibody detects endogenous levels of AurB only when phosphorylated at threonine 232.
ReferencesShindo M., Biochem. Biophys. Res. Commun. 244:285-292(1998).
Tatsuka M., Cancer Res. 58:4811-4816(1998).
Kimura M., Cytogenet. Cell Genet. 82:147-152(1998).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells