Other Names ANAPC1, ANC1, Anaphase promoting complex subunit 1, Cyclosome subunit 1, Mitotic checkpoint regulator, Protein Tsg24, TSG24
All Sites Human: Ser688; Mouse: Ser688
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human APC1 around the phosphorylation site of serine 688 (S-L-SP-P-V).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody againstnon-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity APC1 (Phospho-Ser688) antibody detects endogenous levels of APC1 only when phosphorylated at serine 688.
ReferencesYashi Ahmed, Development, Apr 2002; 129: 1751.
Praveen Kumar, J. Biol. Chem., Sep 2005; 280: 31783 - 31791.
Rebecca A. Green, Mol. Biol. Cell, Oct 2005; 16: 4609 - 4622.
Brian R. Thornton, Genes & Dev., Feb 2006; 20: 449 - 460.