Other Names EC 2.7.10.1, FLK-1, FLK1, Fetal liver kinase 1, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, Protein-tyrosine kinase receptor flk-1, VEGFR-2, VGFR2, Vascular endothelial growth factor receptor 2 precursor, kinase VEGFR-2
All Sites Human: Tyr1054; Mouse: Tyr1052; Rat: Tyr1050
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from humanVEGFR2 around the phosphorylation site of tyrosine 1054 (D-I-YP-K-D).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity VEGFR2 (Phospho-Tyr1054) antibody detects endogenous levels of VEGFR2 only when phosphorylated at tyrosine 1054.
ReferencesTerman B.I., Oncogene 6:1677-1683(1991).
Mitola S., J. Virol. 74:344-353(2000).
Sjoeblom T., Science 314:268-274(2006).