Other Names CD140b, EC 2.7.10.1, PDGF-R-beta, PDGFR, PDGFR-beta, PGFRB, kinase PDGFR-beta
All Sites Human: Tyr1021; Mouse: Tyr1020
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PDGFR β around the phosphorylation site of tyrosine 1021 (N-D-YP-I-I).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PDGFR β (Phospho-Tyr1021) antibody detects endogenous levels of PDGFR β only when phosphorylated at tyrosine 1021.
ReferencesGronwald R.G.K., Proc. Natl. Acad. Sci. U.S.A. 85:3435-3439(1988).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Chi K.D., Oncogene 15:1051-1057(1997).