Other Names CDKN1C, CDN1C, CDNC, Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, KIP2
All Sites Human: Thr310; Mouse: Thr342
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human p57 Kip2 around the phosphorylation site of threonine 310 (E-Q-TP-P-R).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity p57 Kip2 (Phospho-Thr310) antibody detects endogenous levels of p57 Kip2 only when phosphorylated at threonine 310.
ReferencesMatsuoka S., Genes Dev. 9:650-662(1995).
Reid L.H., Cancer Res. 56:1214-1218(1996).
Tokino T., Hum. Genet. 97:625-631(1996).
Lam W.W.K., J. Med. Genet. 36:518-523(1999).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells