Other Names CD119 antigen, CDw119, IFN-gamma-R1, INGR, INGR1, Interferon-gamma receptor alpha chain precursor
All Sites Human: Tyr457; Mouse: Tyr457
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Interferon-γ Receptor α chain around the phosphorylation site of tyrosine 457 (G-YP-D-K-P).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity Interferon-γ Receptor α chain (Phospho-Tyr457) antibody detects endogenous levels of Interferon-γ Receptor α chain only when phosphorylated at tyrosine 457.
ReferencesMungall A.J., Nature 425:805-811(2003).
Stueber D., Biochemistry 32:2423-2430(1993).
Walter M.R., Nature 376:230-235(1995).