Other Names EC 2.7.10.1, ERBB4, HER4, kinase ErbB4, p180erbB4
All Sites Human: Tyr1284; Mouse: Tyr493; Rat: Tyr1284
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human HER4/ErbB4 around the phosphorylation site of tyrosine 1284 (P-E-YP-L-S).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity HER4/ErbB4 (Phospho-Tyr1284) antibody detects endogenous levels of HER4/ErbB4 only when phosphorylated at tyrosine 1284.
ReferencesPlowman G.D., Proc. Natl. Acad. Sci. U.S.A. 90:1746-1750(1993).
Elenius K., J. Biol. Chem. 272:26761-26768(1997).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells