Other Names c-erbB3; ERB3; ERBB3; HER3; kinase ErbB3; Receptor protein-tyrosine kinase erbB-3 precursor; Tyrosine kinase-type cell surface receptor HER3
All Sites Human: Tyr1328; Mouse: Tyr1328; Rat: Tyr1328
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human HER3 around the phosphorylation site of tyrosine 1328(P-D-YP-W-H).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity HER3 (Phospho-Tyr1328) antibody detects endogenous levels of HER3 only when phosphorylated at tyrosine 1328.
ReferencesKraus M.H., Proc. Natl. Acad. Sci. U.S.A. 86:9193-9197(1989).
Plowman G.D., Proc. Natl. Acad. Sci. U.S.A. 87:4905-4909(1990).