Other Names HD3, Histone deacetylase 3, RPD3-2, SMAP45
All Sites Human: Ser424; Mouse: Ser424; Rat: Ser424
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human HDAC3 around the phosphorylation site of serine 424 (K-E-SP-D-V).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity HDAC3 (Phospho-Ser424) antibody detects endogenous levels of HDAC3 only when phosphorylated at serine 424.
ReferencesDangond F., Biochem. Biophys. Res. Commun. 242:648-652(1998).
Yang W.-M., J. Biol. Chem. 272:28001-28007(1997).
Emiliani S., Proc. Natl. Acad. Sci. U.S.A. 95:2795-2800(1998).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells