Other Names Apo-1, CD95, FasL receptor, TNFRSF6, TNR6, apoptosis-mediating surface antigen FAS, tumor necrosis factor receptor superfamily member 6
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human FAS around the phosphorylation site of tyrosine 291 (E-A-YP-D-T).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity FAS (Phospho-Tyr291) antibody detects endogenous levels of FAS only when phosphorylated at tyrosine 291.
ReferencesFred Ramsdell. Int. Immunol., Oct 1994; 6: 1545 - 1553.
Rasheed Ahmad. J. Leukoc. Biol., Jan 2001; 69: 123.
Gabriella Brunlid. Stem Cells, Jul 2007; 10.1634/stemcells.2006-0745.
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Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells