Other Names EC 2.7.10.2, FADK 1, FAK1, Focal adhesion kinase 1, PTK2, Protein- tyrosine kinase 2, pp125FAK
All Sites Human: Ser910; Mouse: Ser948; Rat: Ser913
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human FAK around the phosphorylation site of serine 910 (E-I-SP-P-P).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity FAK (Phospho-Ser910) antibody detects endogenous levels of FAK only when phosphorylated at serine 910.
ReferencesWhitney G.S., DNA Cell Biol. 12:823-830(1993).
Andre E., Biochem. Biophys. Res. Commun. 190:140-147(1993).
Lee S.-T., Oncogene 8:3403-3410(1993).
Matsuya M., J. Biol. Chem. 273:1003-1014(1998).