Other Names EC 2.7.11.24, ERK-3, ERK3, Extracellular signal- regulated kinase 3, MAP kinase isoform p97, MAPK6, MK06, Mitogen-activated protein kinase 6, PRKM4, PRKM6, kinase ERK3, p55-MAPK, p97-MAPK
All Sites Human: Ser189; Mouse: Ser189; Rat: Ser189
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human ERK3 around the phosphorylation site of serine 189 (H-L-SP-E-G).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity ERK3 (Phospho-Ser189) antibody detects endogenous levels of ERK3 only when phosphorylated at serine 189.
ReferencesZhu A.X., Mol. Cell. Biol. 14:8202-8211(1994).
Meloche S., Oncogene 13:1575-1579(1996).
Greenman C., Nature 446:153-158(2007).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells