Other Names EC 2.7.10.1, ERBB1, Epidermal growth factor receptor precursor, Receptor protein-tyrosine kinase ErbB-1, kinase EGFR
All Sites Human: Tyr1069; Mouse: Tyr1069; Rat: Tyr1068
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human EGFR around the phosphorylation site of tyrosine 1069 (Q-R-YP-S-S).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity EGFR (Phospho-Tyr1069) antibody detects endogenous levels of EGFR only when phosphorylated at tyrosine 1069.
ReferencesS Leibl. J. Clin. Pathol., Jul 2005; 58: 700 - 704.
Dhara N. Amin. Cancer Res., Feb 2006; 66: 2173 - 2180.
B. Corkery. ASCO Meeting Abstracts, Jun 2007; 25: 14071.