Other Names DNA- PKcs, DNA-dependent protein kinase catalytic subunit, DNPK1, EC 2.7.11.1, P460, PRKD, PRKDC, XRCC7, kinase DNA-PK
All Sites Human: Ser2056; Mouse: Ser2053
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human DNA-PK around the phosphorylation site of serine 2056 (Y-S-SP-Q-D).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity DNA-PK (Phospho-Ser2056) antibody detects endogenous levels of DNA-PK only when phosphorylated at serine 2056.
ReferencesAllan Y. Chen. AACR Meeting Abstracts, Mar 2004; 2004: 310.
Laura J. Kienker. Nucleic Acids Res., Jul 2000; 28: 2752 - 2761.
Sébastien Soubeyrand. Cancer Res., Mar 2003; 63: 1198 - 1201.