Other Names DNA- PKcs; DNA-dependent protein kinase catalytic subunit; DNPK1; P460; PRKD; PRKDC; XRCC7; kinase DNA-PK
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human DNA-PK around the phosphorylation site of serine 160 (Q-A-SP-Q-G).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity DNA-PK (Phospho-Ser2612) antibody detects endogenous levels of DNA-PK only when phosphorylated at serine 160.
ReferencesHartley K.O., Cell 82:849-856(1995).
Gell D., Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
Anderson C.W., Radiat. Res. 156:2-9(2001).