Other Names C-X-C chemokine receptor type 4, CCR4, CD184 antigen, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, NPYRL, SDF-1 receptor, Stromal cell- derived factor 1 receptor
All Sites Human: Ser339; Mouse: Ser346
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CXCR4 around the phosphorylation site of serine 339 (H-S-SP-V-S).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity CXCR4 (Phospho-Ser339) antibody detects endogenous levels of CXCR4 only when phosphorylated at serine 339.
ReferencesHerzog H., DNA Cell Biol. 12:465-471(1993).
Jazin E.E., Regul. Pept. 47:247-258(1993).
Federsppiel B., Genomics 16:707-712(1993).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells